Chlorination of drinking water linked to increased risk for multiple cancers

Chemical byproducts produced by disinfecting drinking water with chlorine are associated with an elevated risk for both bladder and colorectal cancer, according to a new review published in Environmental Health Perspectives.


In short:

  • Trihalomethane (THM), a byproduct created when chlorine reacts with organic matter in water, is linked to a 33% increased risk of bladder cancer.
  • THM is also linked to a 15% increased risk of colorectal cancer.
  • These risks were found at exposure levels well below the regulatory limits set in both the US and European Union.

Key quote:

“Our findings suggest that [regulatory] limits may fail to protect against cancer in the general population.”

Why this matters:

Assuring that public drinking water supplies are free from bacteria and other infectious agents is critical to maintaining public health. Chlorination has been adopted as a disinfecting method across the globe due to its low cost and accessibility, but animal studies have shown that several of the most common forms of THMs are genotoxic and carcinogenic in rodents. The authors of this study highlight the critical need to improve exposure assessment in order to better understand the potential health effects of commonly used chemicals.

Related EHN coverage:

More resources: Environmental Working Group maintains a state-by-state database of contaminants in drinking water. For more information on THM contamination, visit Tap Water Database: trihalomethanes.

Helte, Emilie et al. for Environmental Health Perspectives vol. 133, 1. Jan. 21, 2025

About the author(s):

Katherine McMahon
Katherine McMahon
Katherine McMahon is a Science Administrative Assistant at Environmental Health Sciences.
Sarah Howard
Sarah Howard
Howard is the Program Manager at Healthy Environment and Endocrine Disruptor Strategies (HEEDS), a program of Environmental Health Sciences.

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