Women with recurrent miscarriages had higher blood levels of certain PFAS compounds, according to new research tracking chemical exposure and pregnancy loss.
Tom Perkins reports for The Guardian.
In short:
- A Chinese study of 200 women found a correlation between elevated PFAS levels and recurrent unexplained miscarriages, with PFHxS and short-chain PFAS among the most strongly linked compounds.
- PFAS chemicals — used in water-resistant and nonstick products — do not break down in nature and are tied to endocrine disruption, cancer, and reproductive harm.
- Despite industry claims that short-chain PFAS are safer, evidence is growing that they may be highly toxic and under-researched.
Key quote:
“It’s a shocking health impact and it further indicates these compounds seem to wreak havoc throughout our body.”
— David Andrews, senior scientist, Environmental Working Group
Why this matters:
PFAS, or per- and polyfluoroalkyl substances, are nearly impossible to avoid. They’re in everything from drinking water to cookware, cosmetics, and clothing. Once in the body, these “forever chemicals” can linger for years, and mounting evidence connects them to serious health concerns, from immune system damage to hormone disruption. Reproductive issues, including miscarriage and birth defects, are among the most troubling. Despite industry claims that newer, short-chain PFAS are less dangerous, researchers continue to find signs of toxicity. Women’s reproductive health is particularly sensitive to hormonal interference, and even low-level exposure may have outsized effects. As PFAS accumulate in people and ecosystems worldwide, understanding their long-term impact grows more urgent, especially for those hoping to start or grow families.
Learn more: What are endocrine-disrupting chemicals?
















