Levels of microplastics in the brain are increasing over time, with high levels found in dementia patients

In a recent paper published by Nature Medicine, researchers examined micro- and nanoplastic (MNP) contamination in brain, liver, and kidney tissue samples collected between 2016 and 2024.


In short:

  • People with dementia had up to ten times the amount of microplastics in their brain tissue than those without dementia.
  • Both liver and brain tissues collected in 2024 had significantly higher concentrations of MNPs than those collected in 2016, with the concentration of plastics in brains increasing by about 50% over the past 8 years.
  • Brain tissue contained 7 to 30 times greater MNP concentrations than liver or kidney samples.

Key quote:

“I have yet to encounter a single human being who says, ‘There’s a bunch of plastic in my brain and I’m totally cool with that.’”

- Study author Matthew Campen, PhD, via University of New Mexico Health Sciences News

Why this matters:

Recent studies have confirmed that microplastics are present in all parts of the human body that have been examined, highlighting an urgent need for solutions that address their potential harm to public health. In this study, MNP concentrations were not influenced by age, sex, or ethnicity, showcasing the ubiquity of plastic pollution and the need to regulate plastic production in order to stop the creation of MNPs at the source.

Related EHN coverage:

More resources:


Nihart, Alexander et al. for Nature Medicine. Feb. 3, 2025

About the author(s):

Katherine McMahon
Katherine McMahon
Katherine McMahon is a Science Administrative Assistant at Environmental Health Sciences.
Sarah Howard
Sarah Howard
Howard is the Program Manager at Healthy Environment and Endocrine Disruptor Strategies (HEEDS), a program of Environmental Health Sciences.

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