Female reproductive disorders are on the rise, and a sweeping review of over 250 studies suggests endocrine-disrupting chemicals are a key contributor.
Pamela Ferdinand reports for U.S. Right to Know.
In short:
- Endocrine-disrupting chemicals (EDCs) such as BPA, phthalates, and PFAS are linked to disrupted puberty, diminished egg quality, and earlier menopause, affecting women’s reproductive health throughout life.
- Evidence from human and animal studies shows these chemicals may interfere with hormonal pathways, damage egg cells, and accelerate reproductive aging, even after exposure ends.
- EDC exposure has also been tied to increased rates of polycystic ovary syndrome (PCOS) and reduced success with fertility treatments like IVF, with researchers calling for stronger regulations to reduce exposure.
Key quote:
"These studies provide causal proof for the numerous reported associations between EDC exposure in adulthood, lower follicle density, and premature menopause.”
— Researchers, Nature Reviews Endocrinology
Why this matters:
Chemicals that disrupt hormones are everywhere — packaging, pesticides, cosmetics, even dust — and they’re affecting human biology in ways scientists are still unraveling. For women, the stakes are especially high. These substances can interfere with hormone function from the womb through adulthood, potentially shortening reproductive lifespans and increasing the risk of disorders like PCOS, infertility, and premature menopause. The effects are often subtle and long-delayed, which makes them hard to detect and regulate. Meanwhile, exposure is nearly universal. Evidence also shows that these chemicals can persist in the environment and in our bodies, compounding across generations. The public health and environmental tolls could be massive, especially if current trends continue without tighter controls on industrial and consumer chemical use.
For more: WATCH: Dr. Shanna Swan on chemicals, hormones and our reproductive health
