Air pollution during midlife may accelerate brain aging, study finds

Exposure to polluted air between ages 45 and 69 is linked to cognitive decline and structural brain changes, new research shows.

Thomas Westerholm reports for Newsweek.


In short:

  • Scientists tracked participants for nearly 30 years, measuring nitrogen dioxide and particulate matter exposure alongside cognitive testing.
  • The strongest effects appeared in midlife, even after adjusting for childhood intelligence and earlier pollution exposure.
  • Dementia cases worldwide are expected to triple by 2050, amplifying the urgency to identify modifiable risk factors like air quality.

Key quote:

"Air pollution has been called the invisible killer and is the number one environmental threat to health in the world."

— Thomas Canning, study lead author

Why this matters:

Air pollution is often framed as a lung or heart hazard, but evidence now shows its reach into the brain. Midlife exposure — when people are working, raising families, and often unaware of invisible risks — may accelerate cognitive aging decades later. With dementia projected to triple worldwide by midcentury, the findings deepen concern about urban living and traffic-heavy environments. The data suggests even low levels of pollutants may chip away at memory and processing speed over time, hinting that the true toll of dirty air on public health may be underestimated. This connection adds pressure to rethink how air quality is regulated and monitored as populations age.

Read more: Air pollution linked to faster brain and body aging in global study

About the author(s):

EHN Curators
EHN Curators
Articles curated and summarized by the Environmental Health News' curation team. Some AI-based tools helped produce this text, with human oversight, fact checking and editing.

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